| Autor: |
Solomko, Z., Sheremet, V., Khmel', M., Avramenko, V., Proshkina, V. |
| Zdroj: |
Chemistry of Heterocyclic Compounds; March 1982, Vol. 18 Issue: 3 p307-310, 4p |
| Abstrakt: |
The chlorination of 4-phenyl-2,3-dihydro-1H-1,5-benzodiazepin-2-one with N-chlorosuccinimide takes place at the methylene group to give mono and diehloro derivatives. In the reaction of the diazepinone with sulfuryl chloride chlorine is incorporated in the 1 or 3 position or in both the 1 and 3 positions, as well as in the para position of the phenyl substituent; in the presence of anhydrous aluminum chloride substitution takes place in the methylene group of the heteroring and in the 8 position of the annelated benzene ring. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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