Condensed imidazo-1,2,4-azines 22. Alkylation of 5H-imidazo[1,2-b]-1,2,4-triazepin-4-ones

Autor: Kruglenko, V. P., Idzikovskii, V. A., Kobets, N. N., Povstyanoi, M. V.
Zdroj: Chemistry of Heterocyclic Compounds; February 1990, Vol. 26 Issue: 2 p201-203, 3p
Abstrakt: Substituted 5H-imidazo[1,2-b]-1,2,4-triazepin-4-ones react with alkyl (alkenyl) halides, 2-chloroethanol, glycerin dichlorohydrin, haloacetic acids, the methyl ester and amide of monochloroacetic acid in a methanol-sodium methylate system to form N(5)-alkylation products, and with hydroxylamino-O-sulfonic acid to form 5-aminoimidazo[1,2-b]-1,2,4-triazepin-4-one.
Databáze: Supplemental Index