Synthesis and study of (2S,4S)-4-arylamino-2-carboxy-5-pyrrolidones

Autor: Krasnov, V. P., Nizova, I. A., Sinitsyna, T. A., Avdyukova, N. V.
Zdroj: Russian Chemical Bulletin; December 1993, Vol. 42 Issue: 12 p2001-2004, 4p
Abstrakt: (2S,4S)-4-Arylamino-2-carboxy-5-pyrrolidones were prepared by hydrolysis of dimethyl (2S,4S)-4-arylamino-N-phthaloylglutamates. The protonation constants of the arylamino group in the synthesized compounds were determined. The pyrrolidone ring is stable in acidic or neutral solutions. The relative stability of the pyrrolidone ring in alkaline solutions was studied by IR spectroscopy.
Databáze: Supplemental Index