Influence of complexation by metal cations on solvophobic retention of crown compounds in reverse-phase high-performance liquid chromatography

Autor: Khorti, A. G., Glibin, E. N., Korshunova, Z. I., Ginzburg, O. F., Ziv, A. D., Nesterov, V. V., Kurenbin, O. I.
Zdroj: Russian Chemical Bulletin; October 1991, Vol. 40 Issue: 10 p1983-1986, 4p
Abstrakt: The retention of crown compounds in reverse-phase HPLC is determined by their ability to bind to cations present in the eluent. The dependence of the retention of crown compounds on concentration of the binding cation has a break. This enables the stability constant of the crown-compound-cation complex to be calculated. The retention of the antitumor antibiotic actinomycin D in 75% MeOH is demonstrated to depend on [Na+] and not on [K+] for concentrations of the latter from 10-6 to 10-1 M.
Databáze: Supplemental Index