5-Fluoro-substituted pyrazoles

Autor: Bargamova, M. D., Motsishkite, S. M., Knunyants, I. L.
Zdroj: Russian Chemical Bulletin; November 1990, Vol. 39 Issue: 11 p2338-2344, 7p
Abstrakt: A preparative method was developed for the synthesis of 5-fluoro-substituted pyrazoles by the reaction of fluoroolefins with substituted hydrazines in the presence of triethylamine. The fluorine atom at the C5 position of the pyrazoles obtained is readily substituted by O-, N-, and S-nucleophiles with the formation of 5-alkoxy-, amino-, mercapto-substituted fluoroalkylpyrazoles.
Databáze: Supplemental Index