Synthesis of 5- and 3-(hydroxyhexafluoroprop-2-yl)-1-(β-D-glucopyranosyl)indoles

Autor: Chkanikov, N. D., Zelenin, A. E., Brondz, N. L., Galakhov, M. V., Kolomiets, A. F., Fokin, A. V.
Zdroj: Russian Chemical Bulletin; October 1986, Vol. 35 Issue: 10 p2093-2098, 6p
Abstrakt: 1.Substituants were introduced into the aromatic ring of indoline glycosides in C-alkylation of l-(tetra-O-acetyl-ß-D-glucopyranosyl)indoline by hexafluoroacetone and methyl trifluoropyruvate.2.Preparative methods were developed for synthesizing 5- and 3-(2-hydroxyhexafluoroprop-2-yl)-1-(3-D-glucopyranosyl)indoles from the C-alkylation products of indoline and indole tetra-O-acetylglucopyranosides.
Databáze: Supplemental Index