Asymmetric synthesis of amino acids by the catalytic reduction of azlactones of protected acylaminoacrylic acids

Autor:	Godunova, L. F., Levitina, E. S., Karpeiskaya, E. I., Klabunovskii, E. I.
Zdroj:	Russian Chemical Bulletin; April 1981, Vol. 30 Issue: 4 p595-600, 6p
Abstrakt:	1.Reductive methanolysis of 2-methyl-4-benzylideneoxazol-5-one in the presence of S-ap-henylethylamine, comprising hydrogenation of the C=C double bond and fission of the oxazolone ring, proceeds without the formation of intermediate products in quantity.2.Z- and E-methyl esters of benzoylaminocinnamic acids on hydrogenation in the presence of a chiral catalytic system based on PdCl2 and S-a-phenylethylamine give the methyl esters of S- and R-benzoylphenylalanine, respectively.3.Hydrogenation of E- and Z-benzoylaminocinnamic acids gives S- and R-benzoylphenylalanine, respectively.
Databáze:	Supplemental Index
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