Reaction of O-ethyl-S-(β-alkylmercaptoethl)-cyclohexylthiophosphonates and their iodomethylates with choline sterases

Autor: Kuzamyshev, V. M., Berkhamov, M. Kh., Godovikov, N. N., Agabekyan, R. S., Kireeva, E. G., Pegova, Z. K., Kabachnik, M. I.
Zdroj: Russian Chemical Bulletin; July 1977, Vol. 26 Issue: 7 p1471-1476, 6p
Abstrakt: O-Ethyl-S-(ß-alkylmercaptoethyl)cyclohexylthiophosphonates are inhibitors of acetylcholinesterase and butyrylcholinesterase with a combinative type of action. The iodomethylates of O-ethyl-S-(ß-alkylmercaptoethyl) cyclohexylthiophosphonates inhibit acetylcholinesterase irreversibly, and butyrylcholinesterase according to a combinative type of inhibition.
Databáze: Supplemental Index
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