Asymmetric hydrogenation of carbonyl group in the presence of modified ruthenium catalyst

Autor: Klabunovskii, E. I., Sokolova, N. P., Vedenyapin, A. A., Talanov, Yu. M.
Zdroj: Russian Chemical Bulletin; August 1971, Vol. 20 Issue: 8 p1694-1695, 2p
Abstrakt: The hydrogenation of acetoacetic ester in the presence of ruthenium, deposited on silica gel, modified with D-tartaric acid at pH 4.2–5.9, yields the (-)-ß-hydroxybutyrate, which possesses optical activity. The highest asymmetric yield is observed when the modifying solution has a pH of 5.5.
Databáze: Supplemental Index