Autor: |
Popov, E. M., Lipkind, G. M., Arkhipova, S. F. |
Zdroj: |
Russian Chemical Bulletin; February 1971, Vol. 20 Issue: 2 p252-257, 6p |
Abstrakt: |
1.N-Methylation of derivatives of the methylamide of N-acetyl-L-alanine leads to a substantial limitation of the conformational freedom of the peptide chain. The shape of the potential surface is extremely sensitive both to the position of the N-methyl group and to its orientation relative to the basic chain.2.The most preferential of the extended forms of these compounds is the conformation with angles of rotation??50°,??250°. The methylamide of N-acetyl-N-methyl-L-alanine in a nonpolar solvent forms a conformation with an intramolecular hydrogen bond with??241°,??117°. |
Databáze: |
Supplemental Index |
Externí odkaz: |
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