| Autor: |
Brunsting, J. R., Bennekers, J. H., Schuil, H. A., Zijlstra, W. G. |
| Zdroj: |
Pflügers Archiv European Journal of Physiology; September 1979, Vol. 381 Issue: 3 p293-295, 3p |
| Abstrakt: |
In dogs in neurolept-anesthesia the successive administration of a- and ß-adrenergic blocking agents and atropine, which should cause the functional equivalent of surgical denervation of the heart, always results in a marked tachycardia. The same is observed in conscious dogs, but not during methoxyflurane anesthesia. Bilateral vagotomy and administration of hexamethonium abolish the tachycardia. These observations demonstrate the presence of a vagally mediated chronotropic effect which becomes manifest when the inhibitory vagal effect is eliminated through blockade of the muscarinic receptors with atropine. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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