Relationship between plasma catecholamines and urinary catecholamine excretion rates in normal subjects and certain diseased states

Autor: Schiffl, Helmut, Weidmann, Peter, Meier, Andreas, Ziegler, Walter H.
Zdroj: Journal of Molecular Medicine; August 1981, Vol. 59 Issue: 15 p837-844, 8p
Abstrakt: Summary Relationships between plasma norepinephrine (PNE) or epinephrine (PE) and urinary norepinephrine (UNE) or epinephrine (UE) excretion rates were studied in 37 normal subjects, 39 patients with benign essential hypertension, 23 with unilateral renal hypertension, and 20 with bilateral renal disease (serum creatinine 2.3±2.6 mg/100 ml). Measurements were also performed after 6 weeks of diuretic treatment in 27 normal subjects and all patients with essential hypertension. In the untreated state, PNE and UNE values were generally normal in essential or unilateral renal hypertension; PNE tended to be decreased in diabetics and increased in bilateral renal disease. Diuretic treatment caused a tendency for slightly increased PNE and UNE. UNE correlated significantly with supine PNE or upright PNE or their mean value, and this relationship appeared to be comparable between untreated normal subjects and the various patient groups, except for a tendency for slightly higher PNE at given UNE values in bilateral renal disease. No significant correlations between UE and PE were apparent in the normal subjects or patient groups.
Databáze: Supplemental Index
Externí odkaz: