Autor: |
Richardson, Carol L., Merritt, W. D., Keenan, T. W., Morré, D. James |
Zdroj: |
Experientia; May 1978, Vol. 34 Issue: 5 p571-572, 2p |
Abstrakt: |
Rat liver contains a particulate (membrane-bound) glycosyl transferase, concentrated in Golgi apparatus fractions, which catalyzes the synthesis of a trisialoganglioside from the ganglioside precursor disialohematoside (GD3). Sialic acid was not incorporated into exogenous GD1afrom CMP-N-acetylneuraminic acid suggesting that GD1ais an endproduct of the monosialoganglioside pathway. Thus, the disialoganglioside pathway may be a primary source of trisialoganglioside and higher ganglioside homologs in adult rat liver. |
Databáze: |
Supplemental Index |
Externí odkaz: |
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