Liver enzyme induction by the anion exchanger resin, Dowex 1×2, in the rat
Autor: | Beyhl, F. E., Granzer, E. |
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Zdroj: | Experientia; September 1977, Vol. 33 Issue: 9 p1194-1196, 3p |
Abstrakt: | Peroral treatment of rats with the anion exchanger resin, Dowex 1×2, for 8 days leads to liver enlargement and increase of alkaline and acid phosphatases, glucose-6-phosphate dehydrogenase, malic enzyme, catalase, and the enzymes of microsomal drug metabolism in the liver. The sequestration of bile acids by this treatment mimics the biochemical effects of clofibrate- and phenobarbital-like drugs in the liver. |
Databáze: | Supplemental Index |
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