| Autor: |
Karakin, E., Nepomnyashchikh, L., Vardosanidze, K., Nekarda, Ya., Patyutko, Yu., Nepomnyashchikh, G., Suderevskii, E., Nechunaev, V., Adon'eva, N., Cheresiz, S., Bochkarev, M. |
| Zdroj: |
Bulletin of Experimental Biology and Medicine; June 1996, Vol. 121 Issue: 6 p610-614, 5p |
| Abstrakt: |
Abstract: Characteristics of the synthesis and Mg-dependent phosphorylation of gastroproteins are studied in intact cells of the mucous coat of the stomach and in the cells of tumor nodes in the same patients. Comparison of polypeptide maps reveals 4 main types of mucous coats which contain p18 (phosphorylated or not), p20, or p22, or no characteristic feature at all. Two kinds of changes, namely, accessory proteins and proteins disappearing from the spectrum, are manifested mainly in extracts of primary tumors as compared to homologous mucous coats of the stomach. Three classes of gastric tumors are distinguished according to the difference between tumor and normal cell polypeptides: I) no difference, II) isolated differences, and III) numerous qualitative and quantitative differences in gastropolypepides and their phosphoforms. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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