| Autor: |
Averbakh, M. M., Litvinov, V. I., Markov, A. N., Il'ina, I. N. |
| Zdroj: |
Bulletin of Experimental Biology and Medicine; February 1980, Vol. 89 Issue: 2 p180-182, 3p |
| Abstrakt: |
The intensity of immunity to tuberculosis and resistance to the disease in the case of infection with the virulent strainMycobacteriumtuberculosis H37Rv were studied in a model of immunologic tolerance induced in CBA mice by injection of a large dose of BCG polyantigen and the immunodepressant cyclophosphamide. Cellular immunity to tuberculosis (tested by the blasttransformation and tuberculin skin tests) was shown not to develop in tolerant animals after BCG vaccination, and vaccination had no protective effect under these circumstances in the group of tolerant mice. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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