Cross reactions in the H-2 system of cytotoxic T-lymphocytes concentrated by adsorption-elution on a target cell monolayer

Autor:	Brondz, B. D., Andreev, A. V., Drizlikh, G. I., Egorova, S. G.
Zdroj:	Bulletin of Experimental Biology and Medicine; February 1979, Vol. 87 Issue: 2 p161-164, 4p
Abstrakt:	Cytotoxic T-lymphocytes (CTL) obtained by immunization in vivo were concentrated by adsorption-elution on a monolayer of corresponding allogeneic target cells (TC). C57BL anti-Ak (anti-KkDd) lymphocytes after separation into anti-Kk and anti-Dd populations, had a crossed cytotoxic effect on H-2d and H-2k TC respectively. B10.D2 anti-B10 (anti-KbDb) lymphocytes cross-reacted with TC of the H-2a and H-2g haplotypes. The results are discussed in terms of views regarding the heterogeneity of clones of CTL or their receptors.
Databáze:	Supplemental Index
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