| Autor: |
Karazhas, N. V., Bykovskii, A. F., Cherepantseva, E. A., Chizhevskaya, V. I., Shevlyagin, V. Ya. |
| Zdroj: |
Bulletin of Experimental Biology and Medicine; December 1978, Vol. 86 Issue: 6 p1639-1642, 4p |
| Abstrakt: |
A line of human embryonic fibroblasts, transformed by Rous sarcoma virus (Schmidt-Ruppin strain) contained and produced Rous virus, as was shown by the complement fixation and immunofluorescent tests, by electron-microscopic investigation, and by the presence of an isotope peak in a sucrose gradient. By its biological properties the synthesized virus differed from the original Schmidt-Ruppin strain for, in particular, the range of cells sensitive to the virus and its protein membrane were changed. Similar data indicating a change in the biological properties of a virus produced in the tissue of an unnatural host also were obtained for polyoma virus, synthesized in human embryonic fibroblasts transformed by it. |
| Databáze: |
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| Externí odkaz: |
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