| Autor: |
Drannik, G. N., Man'ko, V. M., Petrov, R. V., Sologub, P. Ya., Sharykina, N. I. |
| Zdroj: |
Bulletin of Experimental Biology and Medicine; October 1979, Vol. 88 Issue: 4 p1141-1143, 3p |
| Abstrakt: |
Di-iodobenzotepa (DIB) was given per os daily for 3 days in a dose of 25 mg/kg to CBA mice. A decrease in the number of nucleated cells in the thymus by 74% and in the bone marrow by 29% was observed. Experiments with transplantation of lymphocytes from mice treated with DIB into intact or lethally irradiated (CBAxC57BL/6J)F1 mice showed that DIB has no effect on the helper activity of T-lymphocytes but depresses the functional activity of B-lymphocytes and t-lymphocytes, inducing the graft versus host reaction, and of T-suppressor cells. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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