| Autor: |
Gorshunova, L. P., Maksimova-Todorova, V. A., Khizhnyakova, T. M., Nabokova, A. V., Vanag, K. V. |
| Zdroj: |
Bulletin of Experimental Biology and Medicine; November 1978, Vol. 86 Issue: 5 p1480-1482, 3p |
| Abstrakt: |
Of 20 newborn rabbits aged 4–5 days vaccinated intradermally with live smallpox vaccine, six developed manifestations of generalized vaccinia and neuroparalytic complications. Intensive accumulation of the specific antigen in the brain, lungs, spleen and lymph nodes was demonstrated by the fluorescent antibody method. Vaccinia virus was isolated from the same organs. In 14 newborn rabbits killed while clinically healthy, long persistence of attenuated virus was observed in the brain, spinal cord, lungs, spleen, and lymph nodes. The specific antigen was detected by the immunofluorescence method. Vascular disturbances and slight cellular changes were observed in the brain tissue of the vaccinated animals. In sick animals these changes were more marked in character. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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