| Autor: |
Gnezditskaya, É. V., Beletskaya, L. V. |
| Zdroj: |
Bulletin of Experimental Biology and Medicine; November 1978, Vol. 86 Issue: 5 p1540-1543, 4p |
| Abstrakt: |
It was shown by the indirect immunofluorescence method that the lower content of muscle antigens in the myoid cells of the embryonic than in the adult human thymus is due to the higher secretory activity of these cells in the early stages of embryogenesis. Because of the increased secretory activity of the myoid cells the internal medium of the embryonic thymus contains more common antigens with muscle tissue than the adult human thymus. The fact that the functional activity of the myoid cells correlates during individual development with the rate of formation of lymphoid tissue confirms the view that heteroorganic antigens provide the lymphocytes of the thymus with information of the structure of autoantigens necessary for the formation of natural immunologic tolerance to them. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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