Autor: |
Turetskaya, R. L., Avdeev, G. I., Khatuntseva, N. I., Svet-Moldavskaya, I. A., Frank, G. A. |
Zdroj: |
Bulletin of Experimental Biology and Medicine; March 1977, Vol. 83 Issue: 3 p375-377, 3p |
Abstrakt: |
During serial passage of an adenocarcinoma (strain AKTOL) arising as a result of spontaneous malignant change in tissues of the embryonic intestine, transplanted into, syngeneic adult mice, the rate of growth of subcutaneous grafts was increased, the ability to form multiple lung tumor nodules after intravenous inoculation appeared (it was absent in the first passages), and morphological anaplasia of the tumor was increased. These changes, evidence of progression of the tumor, were not directly connected with changes in its immunogenicity. |
Databáze: |
Supplemental Index |
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