| Autor: |
Kozhura, V. L., Molchanova, L. V., Pylova, S. I. |
| Zdroj: |
Bulletin of Experimental Biology and Medicine; August 1976, Vol. 82 Issue: 2 p1161-1164, 4p |
| Abstrakt: |
On the 14th–21st day of the recovery period after hypovolemic hypotension lasting 4 h the total RNA level in the tissue of the gray matter of the brain fell by 20.9% and the DNA level by 13%. In the postmitochondrial supernatant the concentration of prealbumins fell by 26.5%, of a-globulins by 19.2%, and of ?-globulins by 59.8%; the concentration of albumins and ß-globulins increased by 12.6 and 50% respectively. Activity of acid cathepsins rose by 50% and of acid phosphatase by 44%. Activity of total lactate dehydrogenase (LD) and glutamate dehydrogenase did not differ significantly from the control values. However, the LD isozyme spectrum showed a decrease in LD3+4+5 from 31.9 to 14.2%. Analysis of densitograms of electrophoresis in polyacrylamide gel showed changes in the physiocochemical properties of the protein molecules similar to denaturation in nature. The number of Purkinje cells in the cerebellar cortex was 41.3% below the control level. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
|
Full text from SpringerLink