Electroencephalographic changes during general hypothermia and regional cooling of the head

Autor: Sumbatov, L. A., Novoderezhkina, L. B., Lekhtman, A. M.
Zdroj: Bulletin of Experimental Biology and Medicine; December 1975, Vol. 80 Issue: 6 p1415-1418, 4p
Abstrakt: Two series of experiments were carried out on dogs. In series I (80 experiments) the animals were subjected to deep general hypothermia by covering the whole body with finely crushed ice. In series II (29 experiments) isolated deep hypothermia was produced in the head alone by means of a femoral-carotid arterial by-pass and cooling the blood in a heat exchanger. In both series the brain temperature of the animals was reduced to 18–22°C. Comparison of the electroencephalographic changes in the two series showed that cooling the brain leads to a reduction in its electrical activity evenly distributed among all frequencies in the EEG. Predominance of slow waves in the series with generalized hypothermia was not due to the effect of the low brain temperature, as other workers have previously but erroneously maintained, but to the reduction in the cerebral blood flow resulting from the decrease in the minute volume of the circulation accompanying general hypothermia, as other experiments carried out by the writers confirmed.
Databáze: Supplemental Index