Reaction of rat embryonic tissues to mechanical injury and infection with Staphlococcus aureus (strain 209)

Autor: Belen'kaya, S. I.
Zdroj: Bulletin of Experimental Biology and Medicine; July 1975, Vol. 80 Issue: 1 p840-842, 3p
Abstrakt: Healing of skin wounds and the tissue reaction to intrauterine injection ofStaphylococcusaureus (strain 209) were studied in experiments on albino rat embryos. With a horizontal incision, an orthotonic position of the fetus and retraction of the skeletal muscles prevented contraction of the wound and epithelization of its surface. With a vertical incision the wound edges approximated and healing took place without the formation of granulation tissue by epithelization of the wound surface 2 days after the operation. The embryo responded to injection of the pathogenic staphylococcus by a uniform local reaction with predominance of degenerative changes and accumulation of histiocyte-like cells close to some of the colonies. No exudative inflammatory reaction was present either to trauma or to injection of the staphylococcus at all stages of intrauterine life.
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