| Autor: |
Gusev, G. P., Lozhkina, T. K., Matyukhina, L. T., Saltykova, I. A., Sokolova, M. M. |
| Zdroj: |
Bulletin of Experimental Biology and Medicine; March 1975, Vol. 79 Issue: 3 p284-286, 3p |
| Abstrakt: |
The renal excretion of water, Na+, K+, and creatinine was investigated in rats 3 h after administration of a 5% load of 0.9% NaCl solution by the intragastric route. The excretion of Na+ was reduced considerably below the control level in animals receiving trihydroxylupane or heterobetulin 18–20 h before the experiment; the excretion of water, K+, and creatinine was unchanged. After administration of dihydroxylupenal in a dose of 2 mg/100 mg body weight the excretion of Na+ and water was increased. Heterobetulin also increased the excretion of K+ with the urine after administration of a 5% load of 1.25% KCl solution to rats. The results are interesting from the standpoint of the study of the relationship between the structure of substances and their physiological activity. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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