On the participation of the renal tubule in the mechanism of excretion of dysentery antigens by the kidney

Autor: Undritsov, M. I.
Zdroj: Bulletin of Experimental Biology and Medicine; September 1957, Vol. 44 Issue: 3 p1106-1112, 7p
Abstrakt: In 56% of cases primary introduction of dysentery antigen to unimmunized dogs was accompanted by slight excretion of antigens. Excretion of antigens by kidneys after immunization was accelerated by 5–6 times. Increased diuresis in immunized dogs increased antigen excretion correspondingly. Prior to immunization, accelerated diuresis decreased the concentration index, the antigen excretion not being pronounced. Glucose loading, instituted to maximal reabsorption, increased dysentery antigen excretion. They dysentery antigen depressed the maximal reabsorption of glucose in immunized dogs. A certain relation in connection with increased dysentery antigen excretion by kidneys in the process of immunization may be attributed to functional changes of cells of the glomerular apparatus.
Databáze: Supplemental Index