Incorporation of radioactive S15-methionine and C14-glycine into the proteins of whole liver tissue and of liver cell nuclei, at various times after partial hepatectomy

Autor: Perevoshchikova, K. A.
Zdroj: Bulletin of Experimental Biology and Medicine; September 1957, Vol. 44 Issue: 9 p1083-1087, 5p
Abstrakt: Summary The rate of inclusion of S35-methionine and C14-glycine into the proteins of whole tissue and cellular nuclei of rats liver at various periods following partial hepatectomy was investigated. It was established that on the 4th to 6th day following partial hepatectomy the process of inclusion of S35 into the cellular nuclel of the liver was 1.3 to 2 times slower than in the proteins of the tissue regenerate as a whole. The rate of inclusion of S35-methionine into the proteins of the nuclei and the whole tissue of regenerating liver becomes equal on the 15th–20th day. On the second day after partial hepatectomy the products of hydrolysis of ribonucleic acid have no effect on the rate of inclusion of C14-glycine into the proteins of sections of liver regenerate in vitro. A certain increase of inclusion is noted on the 6th day. Hydrolyzate of ribonucleic acid enhances inclusion of C14 from 2 to 21/2 times on the 14th day after the operation.
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