Autor: |
Bax, Willem A., Bruinvels, Anne T., Suylen, Robert-Jan, Saxena, Pramod R., Hoyer, Daniel |
Zdroj: |
Naunyn-Schmiedeberg's Archives of Pharmacology; October 1993, Vol. 348 Issue: 4 p403-410, 8p |
Abstrakt: |
In the present experiments we investigated endothelin (ET) receptors in the human coronary artery, and in ventricular and atrial muscle using quantitative receptor autoradiography. Displacement of [125I]Sf6b (Sarafotoxin S6b) (30 pM)- and [125I]ET-1 (30 pM)-labeled binding sites was studied using ET-1, the ETA receptor selective ligand BQ-123 (cyclo[D-Asp-L-Pro-D Val-L-Leu-D-Trp-]), and the ETB receptor selective ligand [Ala1,3,11,15]ET-1. |
Databáze: |
Supplemental Index |
Externí odkaz: |
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