Karyometrische Studien am cervicalen Drüsenfeld

Autor: Hiersche, H. -D., Inthraphuvasak, J.
Zdroj: Archives of Gynecology and Obstetrics; June 1973, Vol. 215 Issue: 2 p233-243, 11p
Abstrakt: An indirect determination of the size of the nuclei of the cells of the uterus of 93 foete, infants, adolescent girls and grown women at various ages and at different stages of uterine function were carried out with aid of the TGZ- apparatus. It was established that the diameter of the nucleus increased during the growth of the foetus and reaches a maximum of approximately 28 NU before birth. During the course of their growth the group dispersion of the cell nuclei becomes less while their individual dispersion increases. Post partum the diameter of the nuclei increases constantly up to the end of first year of life reaching a size of 20 NU. After this period they remain almost constant during adolescence, the menstrual cycle, gravidity and the menopause. There is therefore a great difference between the functional morphology of the glandular areas of the cervix and those of the corpus uteri. Most probably this difference in the size of the nuclei is caused by endomitosis. To what extent this process is controlled by estrogens or spezific substances (socalled Chalones) remains to be proven.
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