Polyploidization and endomitosis in giant cells of rabbit trophoblast

Autor: Zybina, E. V., Kudryavtseva, M. V., Kudryavtsev, B. N.
Zdroj: Cell and Tissue Research; July 1975, Vol. 160 Issue: 4 p525-537, 13p
Abstrakt: Morphological and cytophotometric investigations have been performed on giant cells of the rabbit trophoblast to reveal a mechanism of nuclei polyploidization and define the level of polyploidy. The character of endomitotic chromosomes is found to differ and depend largely on the degree of nuclei polyploidy. Small chromosomes were found in nuclei with low levels of polyploidy. For highly polyploid nuclei, two stages are distinguished. In the first case condensed chromosomes join into bundles resembling Riesenchromosomen in plants, whereas in the second, decondensed chromosomal threads separate and disperse in the karyoplasm. The splitting does not involve nuclei-forming chromosomes in the region of the nucleolar organiser.
Databáze: Supplemental Index