| Autor: |
Hirsch, Herbert M., Zelickson, Alvin S., Hartmann, J. Francis |
| Zdroj: |
Cell and Tissue Research; May 1965, Vol. 65 Issue: 3 p409-419, 11p |
| Abstrakt: |
Localization of melanin synthesis within the pigment cells of the Cloudman S-91 mouse melanoma was determined by means of a combination of high resolution autoradiography and topographic planimetry. Initial melanin biosynthesis occurred predominantly in the endoplasmic reticulum and associated ribonucleoprotein particles of the melanocytes. By measuring a number of cell organelles and employing the index of “relative specific localization” it could be shown that the nucleus and mitochondria are of little or no importance in the process of melanogenesis. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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