Effect of osmotic pressure on spontaneous afferent discharge in the nerves of the perfused rabbit liver

Autor: Andrews, W. H. Horner, Orbach, Joseph
Zdroj: Pflügers Archiv European Journal of Physiology; January 1975, Vol. 361 Issue: 1 p89-94, 6p
Abstrakt: Rabbit livers were perfused with Krebs solution via the portal vein and small bundles of the hepatic nerve were monitored for spontaneous afferent impulses arising in the liver. The concentration of the Krebs solution was varied by altering the amount of water in which the salts were dissolved. An alteration from 5% more concentrated to 5% more dilute andvice versa did not affect this spontantous discharge. Addition to the Krebs solution of up to 60 mM sucrose, of up to 22 mM mannitol or of 0.8 mM polyethylenglycol 6000 mol. wt. did not alter the frequency of impulses.
Databáze: Supplemental Index