The influence of reserpine pretreatment upon the hemodynamics of dogs during hemorrhagic hypotension

Autor: Seifen, Ernst, Flacke, Werner, Alper, Milton H.
Zdroj: Naunyn-Schmiedeberg's Archives of Pharmacology; January 1964, Vol. 248 Issue: 1 p27-38, 12p
Abstrakt: Pretreatment of dogs with two doses of 0.1 mg/kg reserpine, given 72 and 48 hours before the experiment, did not alter the bleeding volume, i.e., the volume of blood that can be withdrawn before the arterial blood pressure falls to 40 mm Hg, or the maximal volume of blood expelled by the animal during maintained hypotension.
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