Decreased degradation of ββ′ RNA polymerase subunits and abnormal proteins in a mutant E. coli

Autor: Sever, I. S., Kalyaeva, E. S., Danilevskaya, O. N., Gorlenko, Zh. M.
Zdroj: Molecular and General Genetics MGG; December 1982, Vol. 188 Issue: 3 p494-498, 5p
Abstrakt: An opr24 mutation decreasing the degradation of RNA polymerase ßß' subunits was found among the Ts+ revertants of Ts strain carring an rpoC1 mutation which stimulates overproduction of these polypeptides. The opr24 mutation is allele-non-specific, for it decreases the degradation of the mutant ß and ß' subunits, the amberfragment of the ß subunit and the non-mutant ß' subunit. Moreover, opr24 reduces the proteolysis of abnormal proteins containing canavanine.
Databáze: Supplemental Index
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