Structure elucidation with lanthanide-induced shifts 5. Evaluation of the binding ability of various functional groups

Autor: Raber, Douglas J., Johnston, Milton D., Campbell, Catherine M., Guida, Anne, Jackson, F., Janks, Christopher M., Perry, Joseph W., Propeck, Gary J., Raber, Nancy K., Schwalke, Michael A., Sutton, Pamela M.
Zdroj: Monatshefte für Chemie / Chemical Monthly; January 1980, Vol. 111 Issue: 1 p43-52, 10p
Abstrakt: The equilibrium binding constants have been evaluated for the association in CCl4 of the lanthanide shift reagent. Eu(fod)3, with a series of adamantane derivatives containing a variety of different functional groups. It is shown that if steric effects are held constant the binding abilities of the adamantane derivatives exhibit a good correlation with the proton affinities of the methyl analogs containing the same functional groups. The results permit the prediction of binding strength of other functional groups with Eu(dpm)3 as well as with Eu(fod)3 and thus can be of great assistance in planning and interpreting the results of experiments with lanthanide shift reagents.
Databáze: Supplemental Index
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