| Autor: |
Mikhailov, S. N., Padyukova, N. Sh., Panov, K. I. |
| Zdroj: |
Chemistry of Heterocyclic Compounds; February 1989, Vol. 25 Issue: 2 p203-205, 3p |
| Abstrakt: |
A convenient method has been developed for the synthesis of 5'-methyl-2'-desoxyuridines. Chlorination of 5'-O-benzoyl-5'-methyluridines with a mixture of Ph3P and CCl4 in DMF affords the 2'-desoxy-2'-chloro-derivatives, which are then reduced with tributyltin hydride. The crystalline 5'-O-benzoyl-5'-methyl-2'-desoxyuridines were obtained in overall yields of 40–60%. In a similar way, 5'-O-benzoyluridine has given 5'-O-benzoyl-2'-desoxyuridine. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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