Synthesis of carboline bases

Autor: Petrova, M. F., Kaverina, N. S., Men'shikov, G. P.
Zdroj: Chemistry of Heterocyclic Compounds; September 1967, Vol. 3 Issue: 5 p684-685, 2p
Abstrakt: A study has been made of the condensation of serotonin with aldehydes to give the corresponding ß-carboline derivatives. In most cases the reaction was run under biological conditions (pH 5. 4, 36‡). The following aldehydes were reacted: acetaldehyde, butyraldehyde, isobutyraldehyde, benzaldehyde, n-octaldehyde, and formaldehyde. The corresponding ß-carboline derivatives are obtained from the first 5 of these. The reaction with formaldehyde leads to complete resinification.
Databáze: Supplemental Index