Total synthesis and properties of prostaglandins 35. Synthesis and properties of 4-carbomethoxy-alkylaminomethylene-(+)2-oxabicyclo[3.3.0]-6-octen-3-ones

Autor: Dikovskaya, K. I., Mazur, T. V., Turovskii, I. V., Gavars, M. P., Freimanis, Ya. F.
Zdroj: Chemistry of Heterocyclic Compounds; June 1993, Vol. 29 Issue: 6 p635-641, 7p
Abstrakt: Reaction of (+)4-mesyloxymethylene-2-oxabicyclo[3.3.0]-6-octen-3-one with O-amino acids of different lengths gave (+)4-carbomethoxyalkylaminomethylene-2-oxabicyclo[3.3.0]-6-octen-3-ones. For the ?-aminobutyric ester, the corresponding aminomethylene derivative was obtained both in the linear and the cyclic forms. Acylations of the synthesized enamino lactones by acetyl and benzoyl chlorides were investigated.
Databáze: Supplemental Index