Synthesis of alkyl-substituted 2-halo-4-aminomethyl-2-buten-4-olides

Autor: Tyvorskii, V. I., Tishchenko, I. G., Kukharev, A. S., Yushkevich, E. V., Vlasov, S. F.
Zdroj: Chemistry of Heterocyclic Compounds; November 1985, Vol. 21 Issue: 11 p1210-1213, 4p
Abstrakt: The reaction of esters of alkyl-substituted (E)-5-amino-4-hydroxy-2,3,epoxyvaleric acids with some hydrohalic acids gave the corresponding 2-halo-4-amino-methyl-2-buten-4-olides, the hydrochlorides of which have diuretic activity.
Databáze: Supplemental Index