Acetals of lactams and acid amides. 42. Cyclization of dienamino esters, dienamino nitriles, and acylamidines to pyridine derivatives

Autor: Smetskaya, N. I., Mukhina, N. A., Granik, V. G.
Zdroj: Chemistry of Heterocyclic Compounds; June 1984, Vol. 20 Issue: 6 p650-653, 4p
Abstrakt: The reaction of derivatives of alkylidene (cycloalkylidene) cyanoacetic ester, -malo-nodinitrile, and -cyanoacetamide with dimethylformamide diethylacetal with subsequent cyclization of the resulting enamine systems gives derivatives of pyridine, 2-pyridine, and isoquinoline. 2-Amino-3-cyano-4-methylpyridine, which was synthesized by this method, was converted to a pyrido[1,2-a]pyrimidine derivative.
Databáze: Supplemental Index