Acetals of lactams and acid amides. 42. Cyclization of dienamino esters, dienamino nitriles, and acylamidines to pyridine derivatives
Autor: | Smetskaya, N. I., Mukhina, N. A., Granik, V. G. |
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Zdroj: | Chemistry of Heterocyclic Compounds; June 1984, Vol. 20 Issue: 6 p650-653, 4p |
Abstrakt: | The reaction of derivatives of alkylidene (cycloalkylidene) cyanoacetic ester, -malo-nodinitrile, and -cyanoacetamide with dimethylformamide diethylacetal with subsequent cyclization of the resulting enamine systems gives derivatives of pyridine, 2-pyridine, and isoquinoline. 2-Amino-3-cyano-4-methylpyridine, which was synthesized by this method, was converted to a pyrido[1,2-a]pyrimidine derivative. |
Databáze: | Supplemental Index |
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