Acetals of lactams and acid amides. 39. Synthesis of three-ring derivatives of pyrido [l,2-a] pyrimidines on the basis of the reaction of dimethylformamide acetal with dicyanomethylenecycloalkanes

Autor: Granik, V. G., Smetskaya, N. I., Mukhina, N. A., Persianova, I. V., Klimenko, V. G.
Zdroj: Chemistry of Heterocyclic Compounds; September 1983, Vol. 19 Issue: 9 p1027-1030, 4p
Abstrakt: The reaction of dicyanomethylenecyclopentane and -cyclohexane with dimethylformamide diethylacetal was used to synthesize dieneamino nitriles, from which isoquinoline and 2-pyridine derivatives were obtained by treatment with ammonia. The reaction of 3-aminopyridine and 3-aminoisoquinoline derivatives with ethoxymethylenemalonic ester leads to pyrimido [l,2-b] isoquinoline and -2-pyrindene derivatives.
Databáze: Supplemental Index