Synthesis and reactions of 2-amino-3-(ω-chloroaklyl)indoles

Autor: Portnov, Yu. N., Zabrodnyaya, V. G., Voronin, V. G., Kost, A. N.
Zdroj: Chemistry of Heterocyclic Compounds; November 1983, Vol. 19 Issue: 11 p1175-1179, 5p
Abstrakt: The reaction of N-methyl-N-phenyl-N′-(ω-chloro)acylhydrazines with POC13 yields derivatives of 2-amino-3-(ω)-chloroalkyl) indoles. Hydrazides of β-chloropropionic acid were found to exist as the cyclic quaternary 3-oxopyrazolidinium salt. Several reactions involving the nucleophilic substitution of the chlorine atom in N-acylated derivatives of 2-aminoindole were studied.
Databáze: Supplemental Index