Investigation of the recyclization of quaternary salts of papaverine and its structural analogs

Autor: Terenin, V. I., Yudin, L. G., Sagitullin, R. S., Torocheshnikov, V. N., Dulenko, V. I., Nikolyukin, Yu. A., Kost, A. N.
Zdroj: Chemistry of Heterocyclic Compounds; January 1983, Vol. 19 Issue: 1 p66-71, 6p
Abstrakt: The rearrangement of salts of the alkaloid papaverine and its structural analogs under the influence of nucleophilic agents was studied. It is shown that when an alcohol solution of an alkylamine is used as the reagent, replacement of the methoxy group in the 6 position of the isoquinoline ring by an alkylamino group takes place simultaneously with the rearrangement. Rearrangement with retention of the methoxy group can be carried out under the influence of an alkylammonium acetate.
Databáze: Supplemental Index