Pure red cell aplasia: Successful treatment with cyclophosphamide

Autor: Vilan, Jose, Rhyner, Kaspar, Ganzoni, Andreas M.
Zdroj: Annals of Hematology; January 1973, Vol. 26 Issue: 1 p27-34, 8p
Abstrakt: Summary Pure red cell aplasia (PRCA) characterized by complete and selective absence of erythroid precursors was observed in a 60 year old female and unsuccessfully treated with corticosteroids and androgens during 21 months. Cyclophosphamide, in contrast, lead to complete and lasting recovery within 6 weeks. Discussing the immunopathological basis of PRCA the significance of specific anti-erythroblast nuclei antibodies is stressed.
Databáze: Supplemental Index