Pharmacokinetics of temazepam after day-time and night-time oral administration

Autor: Müller, F. O., Dyk, M., Hundt, H. K. L., Joubert, A. L., Luus, H. G., Groenewoud, G., Dunbar, G. C.
Zdroj: European Journal of Clinical Pharmacology; March 1987, Vol. 33 Issue: 2 p211-214, 4p
Abstrakt: The pharmacokinetic disposition of temazepam was compared after a day-time and night-time dose in an open randomised crossover study. Twelve healthy male volunteers received a single oral dose of 20 mg temazepam in a soft gelatine capsule at 0900 h or 2200 h. Blood samples were taken immediately before dosing and at selected times over the 36-h period after each dose.
Databáze: Supplemental Index