Comparison of the pharmacokinetic profile of metaclazepam in old and young volunteers

Autor: Molz, K. -H., Gielsdorf, W., Rasper, J., Jaeger, H., Hausleiter, H. J., Achtert, G., Philipp, P.
Zdroj: European Journal of Clinical Pharmacology; March 1985, Vol. 29 Issue: 2 p247-249, 3p
Abstrakt: A single-centre, open, Phase I-study comparison of the pharmacokinetics of a single dose of metaclazepam 10 mg, a new 1,4-benzodiazepine has been done in 10 older and 20 younger volunteers. No important age-related effect was found on the kinetics of metaclazepam or its N-desmethyl derivative, the principal metabolite in man.
Databáze: Supplemental Index