The use of3H- and14C-labelled tyrosines and product analysis to measure the mono- to diiodination rate constant ratio for iodination by molecular iodine and chloramine-T/I−

Autor:	Baldas, J., Colmanet, S.
Zdroj:	Journal of Radioanalytical and Nuclear Chemistry; April 1989, Vol. 130 Issue: 2 p389-398, 10p
Abstrakt:	Abstract: The observed rate constant ratio,k1obs/k2 obs, for the sequential iodination of L-tyrosine was determined in the concentration range 1.84·10–3 to 1·10–6 M by the use of3H- and14C-labels and product analysis by HPLC. Iodinations by chloramine-T/I– gave (k1 obs/k2 obs)·beta values (beta=the pH dependent factor) in the range 72±3 to 55±2 and molecular iodine iodinations gave values in the range 64±5 to 39±10. It is concluded that molecular iodine is the iodinating species in both cases.
Databáze:	Supplemental Index
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