| Autor: |
Friberg, L. G., Kullander, S., Persijn, J. P., Korsten, C. B. |
| Zdroj: |
Acta Obstetricia et Gynecologica Scandinavica; 1978, Vol. 57 Issue: 3 p261-264, 4p |
| Abstrakt: |
Some human endometrial carcinomas contain receptors for estrogen (E2) and dihydrotestosteron (DHT). Analysis of 50 primary endometrial carcinomas by agar gel electrophoresis revealed a varying receptor pattern, absence of both receptors, sole presence of E2- or DHT-receptor, or presence of both. Highly differentiated tumours often had receptors of both types (7/18) and poorly differentiated tumours most often lacked them (1/10). Primary tumours with metastases (Stages III-IV) seldom had combined receptors, only in 2 cases out of 9. Growth of the tumour down in the cervical canal (Stage II) implied absence of combined receptors in all of the 13 cases studied. In 8 different ovarian tumours, presence of either E2- or DHT-receptors was found in 6. The findings are discussed in relation to hormonal treatment of the disease. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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