Psycho-social stress, insomnia and temazepam: a sleep laboratory evaluation in a “general practice” sample

Autor: Beary, M. D., Lacey, J. H., Crutchfield, M. B., Bhat, A. V.
Zdroj: Psychopharmacology; April 1984, Vol. 83 Issue: 1 p17-19, 3p
Abstrakt: Taking a population of women most of whom were about to seek medication from their general practitioner for stress-induced insomnia, this sleep laboratory study examined — both electro-physiologically and psychologically — the immediate impact of temazepam, at normal prescribed dosage, on sleep. The study was double-blind, controlled with random allocation. Temazepam 20 mg, prepared as a liquid in a soft gelatin capsule, reduced sleep latency and prolonged total sleep time. A reduction in stage shifts to Stages I and II and a reduction in time spent in Stages 0+I suggest more restful sleep. The sleep “architecture” (including REM/NREM cycling, total SWS and REM time) was relatively undisturbed. Temazepam would seem to be effective as a first-line hypnotic for short-term use in stressed patients.
Databáze: Supplemental Index